Staff Bibliographies

Laverne Gugino, MD, PhD, Supervising Physician, joined Sentient Medical Systems in 2003. He received his PhD and MD from the Medical College of Georgia. Since 1988, Dr. Gugino has been the Director of the Intraoperative Neurophysiological Monitoring Division which he founded within the Department of Anesthesia at the Brigham and Women's Hospital, Boston. Dr. Gugino is an Associate Professor of Anesthesia at Harvard Medical School and recently served on the Board of Directors for the American Society of Neurophysiological Monitoring.

 

ORIGINAL REPORTS :

  1. Razumovsky AY, Gugino LD, Owen JH. Advanced neurological monitoring for cardiothoracic and vascular surgery. Seminars Cerebrovasc Dis Stroke. 2006; 5: 141-54.

  2. Razumovsky AY, Gugino LD, Owen JH. Advanced neurologic monitoring for cardiac surgery. Curr Cardiol Rep. 2006; 8(1): 17-22.

  3. Bhattacharyya N, Richardson ME, Gugino LD. An objective assessment of the advantages of retrograde parotidectomy. Otolaryngol Head Neck Surg. 2004; 131(4): 392-6.

  4. Prichep LS, Gugino LD, John ER, Chabot RJ, Howard B, Merkin H, Tom ML, Wolter S, Rausch S, Kox WJ. The patient state index as an indicator of the level of hypnosis under general anesthesia. Br J Anaesth. 2004; 92(3): 393-9.

  5. Chabot RJ, Gugino LD. Patient state index: Titration of delivery and recovery from propofol, alfentanil and nitrous oxide anesthesia. Anesthesiology. 2002; 97(1): 82-9.

  6. Aglio LS, Kraus KH, Desai S, Romero R, Ramirez M, Gugino LD. The use of transcranial magnetic stimulation for monitoring descending spinal cord motor function. Clinical Electroencephalography. 2002; 33(1): 30-41.

  7. Aglio LS, Kraus KH, Desai S, Romero R, Ramirez M, Levy WJ, Gugino LD. Efficacious use of a cap shaped coil for transcranial magnetic stimulation of descending motor paths. Clinical Electroencephalography. 2002; 33(1): 21-9.

  8. Gugino LD, Romero R, Aglio LS, Titone D, Ramirez M, Pascual-Leone A, Grimson E, Weisenfeld N, Kikinis R, Shenton ME. Transcranial magnetic stimulation coregistered with MRI: A comparison of a guided versus blind stimulation technique and its effect on evoked compound muscle action potentials. Clin Neurophysiology. 2001; 112(10): 1781-92.

  9. John Er, Prichep LS, Valdes-Sosa P, Bosch J, Aubert E, Kox W, Tom M, diMichele F, Gugino LD. Invariant reversible QEEG effects of anesthetics. Consciousness and Cognition. 2001; 10: 165-83.

  10. Gugino LD, Chabot RJ, Prichep L, John ER, Formanek V, Aglio LS. Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anesthetized with propofol or sevoflurane. Br J Anaesthesia. 2001; 87(3): 421-8.

  11. Gugino LD, Chabot RJ, Aglio LS, Aranki S, Dekkers R, Maddi R. QEEG changes during cardiopulmonary bypass: Relationship to postooperative neuropsychological function. Clin Electroencephalogr. 1999; 30(2): 53-63.

  12. Potts GF, Gugino LD, Leventon ME, Grimson WEL, Kikinis E, Cote W, Alexander E, Anderson JE, Ettinger GJ, Aglio LS, Shenton ME. Visual hemifield mapping using transcranial magnetic stimulation coregistered with cortical surfaces derived from magnetic resonance images. J Clin Neurophysiol. 1998; 15(4): 344-50.

  13. Danks RA, Rogers M, Aglio LS, Gugino LD, Black P. Patient tolerance of craniotomy performed with the patient under local anesthesia and monitored conscious sedation. J Neurosurgery. 1998; 42(1): 28-36.

  14. Chabot RJ, Gugino LD, Aglio LS, Maddi R, Cote W. QEEG and neuropsychological profiles of patients after undergoing cardiopulmonary bypass surgical procedures. Clin Electroencephalography. 1997; 28(2): 98-105.

  15. Gugino LD, Chabot RJ, Aglio LS, Maddi R, Gosnell J, Aranki S. QEEG and neuropsychological profiles of patients prior to undergoing cardiopulmonary bypass surgical procedures. Clin Electroencephalography. 1997; 28(2): 87-97.

  16. Kraus K, Welch J, Levy J, Gugino LD, Wells M. Partial regeneration of the sciatic nerve in rats enhances motor excitability to magnetic stimulation. Experimental Neurology. 1997; 143: 18-24.

  17. Savage EB, Gugino LD, Starr PA, Black PM, Cohn LH, Aranki SF. Pituitary apoplexy following cardiopulmonary bypass: Considerations for a staged cardiac and neurosurgical procedure (Case Report). European J Cardiothorac Surg. 1994; 8: 333-6.

  18. Kraus KH, Gugino LD, Levy WJ, Cadwell J, Roth BJ. The use of a cap shaped coil for transcranial magnetic stimulation of the motor cortex. J Clin Neurophysiology. 1993; 10(3): 353-62.

  19. Hickey C, Gugino LD, Aglio LS, Mark JB, Maddi R, Lee Son S. Intraoperative somatosensory evoked potentials predict peripheral nervous system injury during cardiac surgery. Anesthesiology. 1993; 78(1): 29-35.

  20. Schwartz RB, LeClercq GT, Jones KM, Sunghee A, Chabot R, Whittemore A, Gugino LD. Predicting cerebral ischemia during carotid endarterectomy using cerebral angiography. Amer J Radiol. 1992; 159: 1057-61.

  21. Gugino LD, Kraus KH, Heino R, Aglio LS, Maddi R. Peripheral ischemia as a comoplicating factor in somatosensory and motor evoked potential monitoring of aortic surgery. (Case Report). J Cardiothorac Vasc Anesth. 1992; 6(6): 715-9.

  22. Gugino LD, Stoney SD, Rowinski M. Raccoon motorsensory cortex organization: III. Motor outflow. Brain Res Bull. 1990; 24: 833-7.

  23. Gugino LD, Stoney SD, Rowinski M. Raccoon motorsensory cortex organization: II. Somatosensory. Brain Res Bull. 1990; 24: 827-32.

  24. Gugino LD, Rowinski M, Stoney SD. Raccoon motorsensory cortex organization: I. Somatosensory inputs to different cytoachitectonic areas. Brain Res Bull. 1990; 24: 819-25.

  25. Raymond S, Steffenson S, Gugino LD, Strichartz G. The role of length of nerve exposed to local anesthetics in impulse blocking action. Anesth Analg. 1989; 68: 563-70.

  26. Gissen AG, Gugino LD, Datta S, Miller J, Covino BG. Effect of fentanyl and sufentanil on peripheral mammalian nerve. Anesth Analg. 1987; 66: 1272-6.

  27. Mark JB, Steinbrook RA, Gugino LD, Maddi R, Hartwell BL, Shemin R, DiSesa V, Rida W. Continuous noninvasive cardiac output monitoring via esophageal doppler ultrasound via esophageal doppler ultrasound cardiac surgery. Anesth Analg. 1986; 65: 1013-20.

  28. Liu PL, Gatt SP, Gugino LD, Covino BG. Esmolol for control of increases in heart rate and blood pressure during tracheal intubation after thiopental and succinylcholine. Canad Anaesth soc J. 1986; 33: 556-62.

  29. Mallampati SR, Gatt SP, Gugino LD, Desai S, Waraksa B, Freiberger D, Liu PL. A clinical sign to predict difficult tracheal intubation: A prospective study. Canad Anaesth Soc J. 1985; 32(4): 429-34.

 

REVIEWS, CHAPTERS, and MONOGRAPHS:

  1. Gugino LD, Aglio LS, Edmonds HL. Monitoring motor system function with transcranial magnetic stimulation. In: Nuwer MR, ed. Handbook of Clinical Neurophysiology. London: Oxford University Press, 2008. (In press).

  2. Gugino LD, Romero R, Ramirez M, Aglio LS, Richardson ME. Transcranial magnetic stimulation in the perioperative period. In: Wasserman E, Epstein C, Ziemann U, Walsh V, Paus T, Lisanby S, eds. Oxford Handbook of Transcranial Stimulation. London: Oxford University Press. 2008; 20: 285-327.

  3. Gugino LD, Aglio LS, Yli-Hankala A. Monitoring the electroencephalogram during bypass surgery. In: Edmonds HL, ed. Seminars in Cardiothoracic and Vascular Anesthesia. New York: Westminster Publications. 2004; 8(2): 61-83.

  4. Gugino LD, Aglio LS, Gonzalez AA. Intraoperative spinal cord path monitoring. In: Pascual-Leone A, Davey N, Wassermann EM, Rothwell J, eds. Handbook of Magnetic Transcranial Stimulation London: Arnold Press. 2001; 18: 197-210.

  5. Gugino LD, Aglio LS, Raymond SA, Cote W, Gonzalez AA, Black PM. Intraoperative cortical function localization techniques. In: Loftus CM, Batjer HH, eds. Techniques in Neurosurgery. Philadelphia: Lippincott-Raven Publishers. 2001; 7(1): 19-32.

  6. Gugino LD, Aglio LS, Potts G, Grimson WEL, Shenton ME, Kikinis R, Alexander E, Ettinger GJ, Cote WA, Leventon ME, Kraus KH, Sprung LJ, Gonzalez AA, Romero R, Black PM. Perioperative use of transcranial magnetic stimulation. In: Loftus CM, Batjer HH, eds. Techniques in Neurosurgery. Philadelphia: Lippincott-Raven Publishers. 2001; 7(1): 33-51.

  7. Gugino LD, Aglio LS, Edmonds H. Neurophysiological monitoring in vascular surgery. In: Gelman S, Thomson DA, eds. Major Vascular Surgery. Baliere's Clinical Anaesthesiology. London: Harcourt Publishers, Ltd. 2000; 14(1): 17-62.

  8. Gugino LD, Aglio LS, Black PM. Cortical stimulation techniques. In: Black PM, Kay A, eds. Operative Neurosurgery. London: Churchill-Livingstone. 2000; 1(7): 85-97.

  9. Gugino LD, Potts G, Aglio LS, Alexander E, Grimson WEL, Kikinis R, Shenton M, Black PM, Ettinger GJ, Cote WA, Leventon M, Sprung LJ. Localization of eloquent cortex using transcranial magnetic stimulation. In: Alexander E, Maciunas RJ, eds. Advanced Neurosurgical Navigation. New York: Thieme Publishers, 1998.

  10. Aglio LS, Gugino LD. Conscious sedation for intraoperative neurosurgical procedures. In: Loftus CM, Batjer HH, eds. Techniques in neurosurgery. Philadelphia: Lippincott-Raven Publishers, 2000.

  11. Gugino LD, Aglio LS, Segal ME, Gonzalez AA, Kraus KH. Use of transcranial magnetic stimulation for monitoring spinal cord paths. Seminars in Spine Surgery. 1997; 9(4): 315-336.

  12. Levy WJ, Kraus K, Gugino LD, Ghaly R, Draughen L, O'Mahoney T. Electrophysiological monitoring: Spinal surgery. In: Andrews RJ ed. Intraoperative Neuroprotection. Baltimore: Williams and Wilkins. 1996; 20: 341-73.

  13. Gugino LD, Chabot RJ. Somatosensory evoked potentials. International Anesthesiology Clinics. 1990; 28(3): 154-64.

  14. Gugino LD. Cadwell- Review of brain mapping- Cadwell Spectrum 32. J Clin Neurophysiol. 1990; 7(4): 556-7. (Review)

  15. Garfield J, Gugino LD. Central effects of local anesthetic agents. In: Strichartz G, ed. Handbook of experimental pharmacology. New York: Verlag Publishers. 1987; 81: 253-84.

 

LETTERS to the EDITOR:

  1. Gugino LD, John ER, Aglio LS. Electroencephalogram as an indicator of cerebral ischemia. Anesth Analg. 1996; 82: 890-1.

  2. Chabot RJ, Gugino LD. Quantitative electroencephalographic monitoring during cardiopulmonary bypass. Anesthesiology. 1993; 78(1): 209-10.

 

THESIS:

  1. Gugino LD. Somatosensory input to motor cortex and corticofugal motor outflow to cervical motoneurons in the raccoon. Augusta: Medical College of Georgia, 1974. (Dissertation)

 

NON-PRINT MATERIAL:

  1. Gugino LD, Aglio LS, Romero R. A review of intraoperative EEG and evoked potential monitoring techniques. In: Bailin M, et al. HEAL: Harvard Electronic Anesthesia Library. Lippincott Williams and Wilkins, 2001.

  2. Aglio LS, Cote W, Gugino LD. Demonstration of the transcranial magnetic brain mapping system. Developed at Brigham and Women's Hospital, Boston, MA. British Broadcast Company, 1996.

  3. Gugino LD, Aglio LS, Cote W. Demonstration of the transcranial magnetic brain mapping system. Developed at Brigham and Women's Hospital, Boston, MA. Scientific america: New Frontiers in Medicine in the 21st Century. Public Television Broadcasting, 1996.

 

ABSTRACTS:

  1. Razumovsky AY, Gugino L, Owen JH. Advanced neuromonitoring for cardiothoracic and vascular surgery. Seminars in Stroke, 2006 (accepted)

  2. Razumovsky A,Y, Gugino L, Owen JH. Advanced neuromonitoring for cardiac surgery. Current Cardiology Reports, 2006 (accepted)

  3. John ER, Gugino LD, Kox WJ, Prichep LS. Changes in gamma (35-50) coherence at loss and return of consciousness during anesthesia with various agents. Poster Presentation at the American Society of Anesthesiologists, New Orleans, LA. Anesthesiology 95(3A):A281, 2001.

  4. Gugino LD, Chabot RJ, Aglio LS, Prichep LS, Formanek V. Patient state index assesses arousal level. Poster Presentation at the American Society of Anesthesiologists, New Orleans, L. Anesthesiology 95(3A):A282, 2001.

  5. Gugino LD, Chabot RJ, Aglio LS, Block-Salisbury E, Prichep LS, John E.R. QEEG changes correlate with quality of emergence from general anesthesia. Poster Presentation at the American Society of Anesthesiologists, New Orleans, LA. Anesthesiology 95(3A):A288, 2001.

  6. Romero R, Gugino LD, Aglio L, Titone D, Ramirez M, Pascual-Leone A, Grimson E, Weisenfeld N, Kikins R, Shenton ME. Benefit of a stereotactic system for spatial specificity of transcranial magnetic stimulation. Presented at the 15th International Congress of Clinical Neurophysiology, Buenos Aires, Argentina, May 16-20, 2001.


 

<empty>